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Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Pediatric optic neuritis

Niphon Chirapapaisan1, Mark S Borchert

  • 1Department of Ophthalmology, Siriraj Hospital, 2 Prannok, Bangkoknoi, Bangkok 10700, Thailand. sincs@mahidol.ac.th

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|June 26, 2008
PubMed

Insights

Pediatric optic neuritis is typically bilateral and affects children equally regardless of gender or race. It is more commonly linked to acute disseminated encephalomyelitis (ADEM) than multiple sclerosis (MS).

Area of Science:

  • Ophthalmology
  • Neurology
  • Pediatrics

Background:

  • Pediatric optic neuritis is an inflammatory condition affecting the optic nerve in children.
  • Understanding its clinical characteristics is crucial for diagnosis and management.

Purpose of the Study:

  • To describe the clinical characteristics of pediatric optic neuritis.
  • To differentiate its presentation in preadolescent versus adolescent age groups.

Main Methods:

  • Retrospective observational case series.
  • Patients ≤12 years old with optic neuritis at Childrens Hospital Los Angeles were analyzed.
  • Patients were divided into preadolescent (<10 years) and adolescent (10-12 years) groups.

Main Results:

  • 17 preadolescents and 14 adolescents were included (31 patients, 48 eyes).
  • Bilateral involvement was more common in preadolescents (65%) than adolescents (43%).
  • Acute disseminated encephalomyelitis (ADEM) was diagnosed in 5 preadolescents; multiple sclerosis (MS) in 2 adolescents. No steroid treatment difference in vision outcomes.

Conclusions:

  • Pediatric optic neuritis shows no gender or racial predilection.
  • The condition is frequently bilateral, particularly in younger children.
  • ADEM is a more common association than MS in pediatric optic neuritis.
Abstract

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