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Influenza

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...

Vaccinations

Vaccinations

Infectious Diseases and Their Occurrence

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

Respiratory Syncytial Virus Disease

Respiratory Syncytial Virus Disease

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Poliomyelitis

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Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...

Pharmacokinetics in Pediatric Patients: Drug Excretion

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Updated: Jul 4, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

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[Influenza in children--an epidemiological problem].

¹Pädiatrische Infektiologie und Vakzinologie, Universitäts-Kinderspital beider Basel (UKBB), Basel. Ulrich.Heininger@ukbb.ch

Therapeutische Umschau. Revue Therapeutique

|June 28, 2008

Summary

Influenza is a severe respiratory illness in children, who are key spreaders of the virus. Universal influenza immunization could benefit both individuals and public health, despite current vaccination challenges.

Area of Science:

Virology
Epidemiology
Pediatrics

Context:

Influenza causes yearly epidemics, primarily affecting the respiratory system.
Children, especially infants and school-aged kids, are frequently impacted and hospitalized due to severe illness and secondary infections.
Children play a crucial role in the community transmission of influenza viruses.

Purpose:

To evaluate the current influenza immunization strategy in Switzerland.
To explore the potential benefits of an universal influenza immunization strategy.
To identify challenges in implementing widespread influenza vaccination.

Summary:

Influenza is a common and potentially severe viral respiratory disease affecting all ages, with children being particularly vulnerable.

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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

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Published on: August 14, 2019

Influenza Virus Propagation in Embryonated Chicken Eggs

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Rapid Molecular Detection and Differentiation of Influenza Viruses A and B

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Published on: January 30, 2017

Children are disproportionately affected by influenza, experiencing high rates of complications and hospitalizations, and are primary vectors for virus transmission.

The study discusses the merits of universal influenza immunization versus the current strategy targeting high-risk groups in Switzerland, acknowledging barriers to acceptance.

Impact:

Highlights the significant burden of influenza in pediatric populations.
Suggests universal influenza vaccination as a potentially more effective public health approach.
Identifies the need to address barriers to vaccination acceptance among healthcare providers and the public.