Related Experiment Video

Updated: Jul 4, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

Respiratory pasteurellosis: infection or colonization?

Laura Muntaner1, Jose M Suriñach, Daniel Zuñiga

  • 1Department of Internal Medicine, Hospital Universitario Vall d'Hebron, Barcelona, Spain. 38535lmm@comb.es

Scandinavian Journal of Infectious Diseases
|June 28, 2008
PubMed

Insights

Pasteurella multocida respiratory infections are rare, typically affecting individuals with compromised health. Early differentiation between colonization and infection is crucial for timely antibiotic therapy.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Pasteurella multocida respiratory infections are infrequent, often seen in patients with pre-existing lung conditions, advanced age, or weakened immune systems.
  • Understanding the clinical and microbiological aspects of these infections is vital for effective management.

Purpose of the Study:

  • To describe the clinical and microbiological features of Pasteurella multocida lower respiratory tract infections.
  • To highlight the importance of distinguishing between colonization and infection for prompt treatment.

Main Methods:

  • Retrospective analysis of 14 patients with Pasteurella multocida isolated from lower respiratory samples.
  • Data collected over a 21-year period (1986-2006).

Main Results:

  • Pasteurella multocida isolation from lower respiratory tract samples occurred in 14 patients over 21 years.
  • Clinical and microbiological data were analyzed to characterize these rare infections.

Conclusions:

  • Respiratory infections caused by Pasteurella multocida are uncommon but significant in specific patient populations.
  • Differentiating colonization from infection is key to initiating appropriate and early antibiotic treatment, improving patient outcomes.

More Related Videos

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae09:12

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae

Published on: January 17, 2014

Related Concept Videos

Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Colonisation of Pathogens01:25

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...