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Effect of arecoline on synaptosomal K+-phosphatase and (Na+ + K+)-ATPase
Acta Biologica Et Medica Germanica
|January 1, 1976
Abstract:
Synaptosomal fractions and synaptosomal membranes from rat brain tissue were prepared and characterized enzymatically. Arecoline increased both the activity of K+-phosphatase in incubated synaptosomal fractions and the (Na+ + K+)-ATPase activity of synaptosomal membranes by 40% and 78%, respectively. This activation of ion transport processes is believed to be associated with increased ACh synthesis produced by arecoline.