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[Discriminant-analytic structure-effect relationship of qualitative biological data. Virostatic effect of
Acta Biologica Et Medica Germanica
|January 1, 1976
Abstract:
"Yes/No" results from the plaque-diffusion inhibition test concerning the virostatic activity of substituted isatin-beta-isothiosemicarbazones against mengo- and vaccinia-viruses can be described discriminant analytically by means of simple substituent constants. The discriminant analysis permits quantitative structure-activity analysis of qualitative and semi-quantitative test data, thus offering a chance for theoretical synthesis optimization already at the level of rough screening.