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Identification and characterization of Bacillus anthracis spores by multiparameter flow cytometry

William C Schumacher1, Craig A Storozuk, Prabir K Dutta

  • 1Department of Chemistry, Ohio State University, Columbus, Ohio 43210, USA.

Applied and Environmental Microbiology
|July 1, 2008
PubMed

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...