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Updated: May 28, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Research on Silver-Based Wound Dressing: An Ontological Analysis.

Prabir K Dutta¹, Thant Syn², Arkalgud Ramaprasad³

¹Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.

Antibiotics (Basel, Switzerland)

|May 27, 2026

Summary

This summary is machine-generated.

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This study introduces an ontology to analyze silver in wound dressings research. While silver nanoparticles dominate academic papers, other silver forms show more clinical testing for wound healing.

Area of Science:

Biomedical Engineering
Materials Science
Nanotechnology

Background:

Silver exhibits antimicrobial properties, driving research in wound dressings.
Existing literature reviews use qualitative or bibliometric analyses.
A novel ontological approach is proposed for analyzing this research field.

Purpose of the Study:

To develop and apply an ontology for analyzing the research landscape of silver in wound dressings.
To map and visualize the temporal trends and characteristics of silver-based wound dressing research.

Main Methods:

A Scopus database search identified 4711 articles on silver in wound dressings.
An ontology was constructed, deconstructing the research problem into key dimensions.
A Convolutional Neural Network (CNN) was trained to map the article population using the ontology.

Keywords:

artificial intelligence (AI)chronic wounds neural network ontology regulations research history research pathways research roadmap silver in health and medicine systematic review systemic review

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Last Updated: May 28, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Main Results:

3079 articles focused on silver and wound dressings; three silver classes were identified: nanoparticles (78%), inorganic ions (7%), and organics (15%).
Silver nanoparticle research has grown exponentially since the early 2000s, with a focus on in vitro studies (54%).
Silver-organic and inorganic silver-ion species show more prominent animal (30%, 43%) and human testing (38%, 43%) compared to AgNPs (3%).

Conclusions:

The ontological analysis provides a novel visualization of the entire research field.
Temporal trends reveal that silver nanoparticles lag in clinical applications despite robust academic research.
The ontology offers insights into the current state and future direction of silver in wound dressing research.