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Rice solution and World Health Organization solution by gastric infusion for high stool output diarrhea
F Mota-Hernández1, D Bross-Soriano, M L Pérez-Ricardez
1Servicio de Hidratación Oral, Hospital Infantil de México, Frederico Gómez, México, D.F.
Insights
A novel rice flour solution effectively treated acute diarrhea in infants with high stool output, leading to faster rehydration compared to standard methods. This rice flour treatment offers a promising alternative for managing severe pediatric diarrhea.
Area of Science:
- Pediatrics
- Gastroenterology
- Nutrition
Background:
- Acute diarrhea in children, particularly with high stool output, poses a significant rehydration challenge.
- Standard oral rehydration solutions may be less effective in cases of severe fluid loss.
Purpose of the Study:
- To evaluate the efficacy of a rice flour solution compared to standard World Health Organization (WHO) rehydration solution in children with acute diarrhea and high stool output.
- To assess the impact of different rehydration methods on the rate and success of fluid restoration.
Main Methods:
- A randomized controlled trial involving 66 children aged 1-18 months with high stool output ( > 10 mL/kg/hour).
- Three groups were formed: Group 1 received a rice flour solution, Group 2 received WHO solution via gastric infusion, and Group 3 received WHO solution orally.
- Stool output and rehydration time were primary outcome measures.
Main Results:
- The rice flour solution group (Group 1) showed the greatest decrease in stool output.
- 100% of patients in Group 1 were rehydrated in an average of 3.3 hours.
- Rehydration was achieved in 73% of Group 2 (4.3 hours) and 69% of Group 3 (4.9 hours).
- No complications were reported in any group.
Conclusions:
- A rice flour solution is an effective treatment for acute diarrhea in children experiencing high stool output.
- This alternative rehydration strategy facilitates quicker and more complete fluid restoration.
- Rice flour solution presents a safe and effective option for managing severe pediatric diarrhea.
Abstract:
We sought to determine the efficacy of three different types of treatment in children with acute diarrhea who, during the oral rehydration period, had high stool output (greater than 10 mL/kg per hour). Sixty-six children, aged 1 to 18 months, with an average stool output of 22.6 mL/kg per hour were randomly distributed into three groups: group 1 received a rice flour solution, group 2 received the World Health Organization rehydration solution by gastric infusion, and group 3 continued to receive this solution orally. In all three groups, a decrease in stool output was observed, with the higher decrease observed in group 1 patients. Such a decrease facilitated rehydration of all 22 patients in group 1 (100%) in 3.3 +/- 1.5 hours, 16 (73%) in group 2 in 4.3 +/- 2.1 hours, and 15 (69%) in group 3 in 4.9 +/- 2.0 hours. No complications were observed. These data indicate that the rice flour solution is effective in children with high stool output diarrhea.