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Physical immobilization characteristics of a hybridoma in a glass bead packed-bed reactor

O T Ramírez1, R Mutharasan

  • 1Department of Chemical Engineering, Drexel University, Philadelphia, Pennsylvania 19104, USA.

Biotechnology and Bioengineering
|March 1, 1989
PubMed
Abstract

No abstract available in PubMed .

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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