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Plasmid Stability Analysis with Open-Source Droplet Microfluidics
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Retention of plasmid bearing cells by immobilization

E L Walls, J L Gainer

    Biotechnology and Bioengineering
    |August 20, 1989
    PubMed
    Abstract

    No abstract available in PubMed .

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    Plasmids are extrachromosomal DNA molecules found in bacteria, archaea, and some eukaryotic microbes like yeast. These small, circular DNA structures typically contain fewer than 30 genes, although some may exist linearly. Plasmids vary in their number within a cell, known as copy number. Single-copy plasmids are present in one copy per cell and multi-copy plasmids are present in multiple copies, reaching over 100 copies per cell.Plasmids usually replicate independently of the chromosomal DNA...

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