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A novel HLA-A*3315 allele identified by haplotype-specific extraction and sequence-based typing
1Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Tissue Antigens
|July 1, 2008
Abstract:
A novel HLA-A*33 variant allele, A*3315, was identified in three Korean siblings. This allele shows only one nucleotide difference from A*330301 in exon 4 at nucleotide position 727 (codon 219 CGG-->TGG), resulting in an amino acid change from arginine (R) to tryptophan (W).
