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Updated: Jul 4, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Chemical constituents of Changium smyrnioides]
Dong-chun Ren1, Shi-hui Qian, Nian-yun Yang
1Jiangsu Institute of Traditional Chinese Medicine, Nanjing 210028, China.
Objective:
To study chemical constituents of Changium smyrnioides Wolff.
Methods:
The chemical components were isolated and purified by silica gel column and recrystallization. The chemical structures were elucidated on the basis of physico-chemical properties and spectral data.
Results:
Ten compounds were isolated and identified as lignoceric acid (1), beta-sitosterol (2), stigmasterol (3), 5-hydroxy-8-methoxypsoralen (4), glycerylmonopalmitate (5), L-pyroglutamic acid (6), succinic acid (7), vanillic acid-4-O-beta-D-glucopyranoside (8 ), vanillic acid (9), daucosterol (10).
Conclusion:
Compounds 1, 4, 5, 6, 8 and 9 are obtained from the plant for the first time.
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