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Updated: Jul 4, 2026
09:31
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
[Epithelioid renal angiomyolipoma]
Igor Azurmendi Arin1, Roberto Llarena Ibarguren, Jorge García-Olaverri Rodríguez
1Servicio de Urología, Hospital de Cruces, Baracaldo, Vizcaya, España. igorazurmendi@hotmail.com
Archivos Espanoles De Urologia
|July 3, 2008
Summary
This study identifies a rare epithelioid angiomyolipoma variant in a patient with Bourneville's disease. This finding highlights the importance of considering this specific renal tumor type, especially in phakomatosis patients.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Angiomyolipomas are benign kidney tumors, but rare variants can exhibit aggressive behavior.
- Bourneville's disease (tuberous sclerosis complex) is associated with an increased risk of renal tumors, including angiomyolipomas.
Observation:
- A 17-year-old female with Bourneville's disease presented with a solid renal mass on CT scan.
- The mass, initially suspicious for carcinoma, was found adjacent to smaller, typical angiomyolipomas.
Findings:
- Histopathological examination and immunohistochemistry confirmed the 4 cm renal mass as an epithelioid angiomyolipoma.
- The tumor was HMB45 positive and negative for vimentin and keratin, distinguishing it from renal cell carcinoma.
Implications:
- The existence of epithelioid angiomyolipoma should be considered in patients with phakomatosis, even with coexisting typical angiomyolipomas or suspicion of adenocarcinoma.
- While surgical indications are similar to other renal masses, stricter follow-up is warranted due to the potential for dissemination of this rare variant.
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