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Updated: Jul 4, 2026
A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Primary vaginal melanoma: a case report and literature review
1Department of Obstetrics and Gynecology, University of Wuerzburg, Wuerzburg, Germany. melanie_weigand@hotmail.de
Background:
Malignant melanoma of the vagina is a rare malignancy associated with high risk of recurrence, distant metastasis and short survival time. Due to the rarity of the disease, no prospective studies or validated treatment recommendations exist.
Case:
We describe the case of a 54-year-old patient with a locally advanced melanoma located on the anterior vaginal wall. At the time of diagnosis there was no evidence of nodal or distant metastasis.
Conclusion:
In view of retrospective data in the literature, we treated the patient with colpectomy in terms of a wide local excision only. A more radical approach, adjuvant radio- or chemotherapy did not seem to be justifiable since there are no data demonstrating prolonged survival.
