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Updated: Jul 4, 2026

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
Published on: October 2, 2021
Exact and efficient signal reconstruction in frequency-domain optical-coherence tomography
Chandra Sekhar Seelamantula1, Martin L Villiger, Rainer A Leitgeb
1Laboratoire d'imagerie biomédicale, Ecole polytechnique fédérale de Lausanne, Switzerland. chandrasekhar.seelamantula@epfl.ch
Abstract:
We address the problem of tomogram reconstruction in frequency-domain optical-coherence tomography. We propose a new technique for suppressing the autocorrelation artifacts that are commonly encountered with the conventional Fourier-transform-based approach. The technique is based on the assumptions that the scattering function is causal and that the intensity of the light reflected from the object is smaller than that of the reference. The technique is noniterative, nonlinear, and yields an exact solution in the absence of noise. Results on synthesized data and experimental measurements show that the technique offers superior quality reconstruction and is computationally more efficient than the iterative technique reported in the literature.
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