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Updated: Jul 4, 2026

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Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
[Epididymitis after prostatic adenomectomy--24-years observations]
Bołeslaw Kuzaka1, Tomasz Borkowski, Piotr Kuzaka
1Katedra i Klinika Urologii Akademii Medycznej w Warszawie.
Summary
Postoperative epididymitis following prostate surgery has decreased significantly. Improved surgical techniques and antibiotic therapy reduce infection rates, making routine prophylactic vasectomy unnecessary.
Area of Science:
- Urology
- Surgical Outcomes
- Infectious Disease
Context:
- Benign prostatic hyperplasia (BPH) is a common condition requiring surgical intervention.
- Postoperative epididymitis is a potential complication of BPH surgery.
- Evaluating trends and risk factors for postoperative epididymitis is crucial for improving patient care.
Purpose:
- To retrospectively analyze the incidence of postoperative epididymitis in patients undergoing suprapubic and transurethral adenomectomy for BPH.
- To identify factors associated with the development of postoperative epididymitis.
- To assess the historical trend of postoperative epididymitis and the role of prophylactic vasectomy.
Summary:
- A 24-year retrospective review of 6811 BPH patients revealed a low incidence of acute postoperative epididymitis (0.64%).
- Incidence varied by surgical approach: transvesical adenomectomy (1.53%), retropubic surgery (1.09%), and transurethral resection of the prostate (TURP) (0.11%).
- Postoperative epididymitis correlated with urinary tract infections (UTIs), predominantly caused by Gram-negative bacteria. No difference in incidence was observed between patients with and without prophylactic vasectomy.
Impact:
- Significant decrease in postoperative epididymitis incidence over two decades, linked to advancements in surgical techniques and reduced catheterization duration.
- Shorter catheterization periods minimize UTIs, thereby reducing the occurrence of postoperative epididymitis.
- Antibiotic therapy effectively treats most cases (70.45%), and routine prophylactic vasectomy is no longer indicated for BPH surgery.
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