A regio- and stereocontrolled approach to pyranosyl C-nucleoside synthesis
Philip Redpath1, Simon Macdonald, Marie E Migaud
1Respiratory CEDD, Stevenage SG12NY, UK.
Organic Letters
|July 5, 2008
Abstract:
Six novel diastereomerically pure C-nucleosides have been synthesized from nonchiral starting materials, using the ene/intramolecular Sakurai cyclization reaction demonstrating a simple, general, and stereocontrolled approach to pyranosyl C-nucleosides.
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