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Studies of Chaperone-Cochaperone Interactions using Homogenous Bead-Based Assay
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Potential for modulation of the hydrophobic effect inside chaperonins

Jeremy L England1, Vijay S Pande

  • 1Department of Physics, Stanford University, Stanford, California 94305, USA.

Biophysical Journal
|July 5, 2008
PubMed
Summary

Chaperonins, protein-folding machines, may enhance protein folding by reorganizing water molecules. This creates a microenvironment that strengthens the hydrophobic effect, a key driver for protein folding.

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