Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Special considerations while measuring pulse01:13

Special considerations while measuring pulse

Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laning and clustering transitions in driven binary active matter systems.

Physical review. E·2018
Same author

Probing lepton flavour violation via neutrinoless [Formula: see text] decays with the ATLAS detector.

The European physical journal. C, Particles and fields·2017
Same author

Search for massive WH resonances decaying into the [Formula: see text] final state at [Formula: see text][Formula: see text].

The European physical journal. C, Particles and fields·2017
Same author

Measurement of the centrality dependence of the charged-particle pseudorapidity distribution in proton-lead collisions at [Formula: see text] TeV with the ATLAS detector.

The European physical journal. C, Particles and fields·2017
Same author

Search for new phenomena in events with at least three photons collected in <i>pp</i> collisions at [Formula: see text] = 8 TeV with the ATLAS detector.

The European physical journal. C, Particles and fields·2017
Same author

Measurements of the [Formula: see text] production cross section in lepton+jets final states in pp collisions at 8 [Formula: see text] and ratio of 8 to 7 [Formula: see text] cross sections.

The European physical journal. C, Particles and fields·2017
Same journal

Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture.

Biotechnology and bioengineering·2026
Same journal

LLM-Guided Parameter Optimization for Mechanistic CHO Cell Bioreactor Models.

Biotechnology and bioengineering·2026
Same journal

Three-Dimensional-Printed Polylactic Acid Scaffolds Coated With a Paeonol-Incorporated Gelatin/Bioactive Glass Composite Layer for Enhanced Osteogenic Performance.

Biotechnology and bioengineering·2026
Same journal

Recent Progress in Antimicrobial Peptides (AMPs) Towards Enhanced Selectivity and Reduced Cytotoxicity by Molecular Engineering.

Biotechnology and bioengineering·2026
Same journal

mZVI-Enhanced Mixed Nitrogen Removal in Klebsiella oxytoca via Coordinated Electron Transfer and Metabolic Reprogramming.

Biotechnology and bioengineering·2026
Same journal

Growth Model for Continuous Culture of a Hydrogen-Oxidizing Bacterium, Hydrogenophilus thermoluteolus Strain TH-1.

Biotechnology and bioengineering·2026
See all related articles

Related Experiment Video

Updated: Jul 3, 2026

Real-Time DC-dynamic Biasing Method for Switching Time Improvement in Severely Underdamped Fringing-field Electrostatic MEMS Actuators
11:44

Real-Time DC-dynamic Biasing Method for Switching Time Improvement in Severely Underdamped Fringing-field Electrostatic MEMS Actuators

Published on: August 15, 2014

Measuring kLa with randomly pulsed dynamic method.

L Gauthier1, J Thibault, A LeDuy

  • 1Department of Chemical Engineering, Laval University, Ste-Foy, Quebec, Canada, G1K 7P4.

Biotechnology and Bioengineering
|April 15, 1991
PubMed
Summary
This summary is machine-generated.

This study determined the oxygen transfer coefficient using a novel dynamic method. The technique shows promise for process control but requires further development for real-time fermentation monitoring.

More Related Videos

Dynamic Electrochemical Measurement of Chloride Ions
07:32

Dynamic Electrochemical Measurement of Chloride Ions

Published on: February 5, 2016

Quantification and Size-profiling of Extracellular Vesicles Using Tunable Resistive Pulse Sensing
12:01

Quantification and Size-profiling of Extracellular Vesicles Using Tunable Resistive Pulse Sensing

Published on: October 19, 2014

Related Experiment Videos

Last Updated: Jul 3, 2026

Real-Time DC-dynamic Biasing Method for Switching Time Improvement in Severely Underdamped Fringing-field Electrostatic MEMS Actuators
11:44

Real-Time DC-dynamic Biasing Method for Switching Time Improvement in Severely Underdamped Fringing-field Electrostatic MEMS Actuators

Published on: August 15, 2014

Dynamic Electrochemical Measurement of Chloride Ions
07:32

Dynamic Electrochemical Measurement of Chloride Ions

Published on: February 5, 2016

Quantification and Size-profiling of Extracellular Vesicles Using Tunable Resistive Pulse Sensing
12:01

Quantification and Size-profiling of Extracellular Vesicles Using Tunable Resistive Pulse Sensing

Published on: October 19, 2014

Area of Science:

  • Chemical Engineering
  • Bioprocess Engineering
  • Process Control

Background:

  • Accurate determination of the oxygen transfer coefficient (kLa) is crucial for optimizing aerobic bioprocesses.
  • Traditional gassing-out methods for kLa determination can be time-consuming and labor-intensive.
  • Developing reliable and efficient methods for monitoring kLa is essential for process control and scale-up.

Purpose of the Study:

  • To evaluate a randomly pulsed dynamic method for determining the overall oxygen transfer coefficient (kLa) in a mechanically agitated vessel.
  • To compare the reliability and reproducibility of the pulsed dynamic method against the traditional gassing-out method.
  • To assess the potential of the pulsed dynamic method for on-line monitoring of kLa in bioprocesses.

Main Methods:

  • Utilized a mechanically agitated vessel with a gas stream switched randomly between air and nitrogen using a pseudo-random binary sequence.
  • Employed process control techniques for system identification to determine the transfer function.
  • Conducted experiments in water to assess method performance.

Main Results:

  • The randomly pulsed dynamic method demonstrated good reliability and reproducibility in water compared to the traditional gassing-out method.
  • The method successfully determined the overall oxygen transfer coefficient.
  • The procedure is analogous to standard techniques used in process control for system identification.

Conclusions:

  • The randomly pulsed dynamic method offers a reliable and reproducible alternative for determining the oxygen transfer coefficient in mechanically agitated systems.
  • While effective in water, further advancements are necessary to adapt this method for real-time, on-line monitoring of kLa during fermentation.
  • This technique holds potential for improving process understanding and control in bioprocessing applications.