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Updated: Jul 3, 2026

Measurement of the Pressure-volume Curve in Mouse Lungs
Published on: January 27, 2015
Respiratory system model for quasistatic pulmonary pressure-volume (P-V) curve: generalized P-V curve analyses
R Amini1, T A Barnes, A Savran
1Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA.
Abstract:
A normalized P-V curve is proposed for quantitative comparisons of quasistatic P-V curves from different sources, including data from different investigators, airway pressure-volume curves versus transpulmonary pressure-volume curves, normal versus injured respiratory system, and animal tests versus clinical data. Similarities and differences among five different data groups we analyzed are shown to be quantified through the nondimensional pressure range of an individual data set, combined with the magnitudes of two nondimensional parameters of the inflation limb, derived from a respiratory system model previously reported.
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