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Updated: Jul 3, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Recurrent rhinitis and pulmonary infections revealing celiac disease: case report]
M Kallel-Sellami1, L Laadhar, M Zitouni
1Laboratoire d'immunologie, Hôpital La Rabta, Tunis, Tunisia.
Abstract:
Celiac disease is associated with a number of extra-gastrointestinal features such as hepatitis, arthralgia, and recurrent foetal loss. However respiratory involvement is an extremely rare disorder. We report a case of celiac disease revealed by bronchiectasia in a 39-year-old man. The patient reported a history of recurrent pulmonary infections and intermittent intestinal symptoms in childhood. Wegner granulomatosis was initially suspected because of rhinopulmonary involvement. Serum's patient was tested for ANCA and anti-tissue antibodies. The latest test was performed on histological sections from rat and revealed the presence of anti-reticulin antibodies. Further testing, for anti-tissue transglutaminase and anti-endomysium antibodies, revealed positive results. Celiac disease was confirmed by histological examination of intestinal biopsy. Pulmonary symptoms were improved on a gluten free diet suggesting a causal relationship between celiac disease and respiratory symptoms.
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