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Related Experiment Video

Updated: Jul 3, 2026

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

Sickle cell hepatopathy.

Ranjana Bandyopadhyay¹, Sanjay K Bandyopadhyay, Anita Dutta

¹Department of Pathology, Medical College, Kolkata 73, India. drsanjay_b@rediffmail.com

Indian Journal of Pathology & Microbiology

|July 8, 2008

Summary

This summary is machine-generated.

Sickle cell hepatopathy presents a spectrum of liver conditions in sickle cell disease patients. This case highlights a unique presentation of severe cholestasis and liver injury in a young adult.

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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

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Last Updated: Jul 3, 2026

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

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Published on: November 5, 2019

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Area of Science:

Hepatology
Hematology
Pathology

Background:

Sickle cell hepatopathy encompasses a range of liver complications in sickle cell disease (SCD).
These complications vary from mild hepatic syndromes to life-threatening conditions like intrahepatic cholestasis and hepatic sequestration.

Observation:

A case study of a 26-year-old male with homozygous sickle cell disease is presented.
The patient exhibited an unusual hepatic presentation.

Findings:

Histopathological examination revealed characteristic findings of cholestasis, portal inflammation, and sinusoidal dilatation.
These findings are indicative of significant liver injury in the context of sickle cell disease.

Implications:

This case underscores the diverse and severe hepatic manifestations possible in sickle cell disease.
Understanding these presentations is crucial for timely diagnosis and management of sickle cell hepatopathy.