Related Experiment Video
Updated: Jul 3, 2026

09:29
An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
Published on: May 13, 2020
Exposure modeling of engineered nanoparticles in the environment
Nicole C Mueller1, Bernd Nowack
1Technology and Society Laboratory, Empa-Swiss Federal Laboratories for Materials Testing and Research Lerchenfeldstrasse 5, CH-9014 St. Gallen, Switzerland.
Environmental Science & Technology
|July 9, 2008
Summary
This study modeled environmental nanoparticle release, finding nano-TiO2 concentrations in water may pose risks. Carbon nanotubes (CNT) and nano silver (nano-Ag) showed lower environmental risk quotients.
Area of Science:
- Environmental Science
- Nanotechnology
- Risk Assessment
Background:
- Engineered nanoparticles (ENPs) are increasingly used in products.
- Understanding their environmental release and potential risks is crucial.
Purpose of the Study:
- To model environmental release quantities of engineered nanoparticles (ENPs) using a life-cycle perspective.
- To assess potential environmental risks of nano silver (nano-Ag), nano titanium dioxide (nano-TiO2), and carbon nanotubes (CNT).
Main Methods:
- Substance flow analysis in Switzerland, considering production volumes, product allocation, release rates, and environmental flow coefficients.
- Comparison of Predicted Environmental Concentrations (PEC) with Predicted No Effect Concentrations (PNEC) to calculate risk quotients (PEC/PNEC).
Main Results:
- Environmental concentrations of ENPs varied significantly based on product life cycles.
- Predicted Environmental Concentrations (PEC) for nano-TiO2 in water were near or exceeded Predicted No Effect Concentrations (PNEC).
- Risk quotients for CNT and nano-Ag were substantially below 1, indicating lower immediate risk.
Conclusions:
- This study provides a quantitative framework for assessing environmental risks of ENPs.
- Nano-TiO2 warrants further detailed environmental risk assessment due to potential concerns in aquatic environments.

