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Related Experiment Videos

Diuretic Doppler sonography in postnatal hydronephrosis.

J M Palmer1, K K Lindfors, R C Ordorica

  • 1Department of Urology, University of California, Davis, Sacramento.

The Journal of Urology
|August 1, 1991
PubMed
Summary

Diuretic Doppler sonography effectively differentiates obstructive hydronephrosis in children. Elevated renal resistive indexes post-furosemide indicate significant obstruction, aiding diagnosis.

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Area of Science:

  • Pediatric Nephrology
  • Diagnostic Imaging
  • Medical Ultrasound

Background:

  • Hydronephrosis in children requires accurate differentiation between obstructive and non-obstructive causes.
  • Standard diagnostic studies may not always definitively distinguish functionally significant obstruction.

Purpose of the Study:

  • To evaluate the utility of diuretic Doppler sonography in assessing renal resistive indexes for hydronephrosis in pediatric patients.
  • To determine if furosemide administration can enhance the detection of renal obstruction.

Main Methods:

  • Renal resistive indexes were measured using Doppler sonography in 12 children.
  • Measurements were taken at baseline, and 10 and 30 minutes after oral hydration, bladder catheterization, and furosemide administration (1 mg/kg).

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  • Comparison was made between obstructed and non-obstructed kidneys.

    • Main Results:

    • Diuretic administration did not significantly alter renal resistive indexes in non-obstructed kidneys.
    • Obstructed kidneys showed significantly elevated 10-minute post-diuretic renal resistive indexes compared to non-obstructed kidneys (p < 0.001).
    • Unilaterally obstructed kidneys demonstrated at least a 15% increase in renal resistive indexes post-diuretic.

    Conclusions:

    • Diuretic Doppler sonography is a valuable tool for differentiating functionally significant hydronephrosis from non-obstructive causes in children.
    • The post-furosemide renal resistive index is a sensitive indicator of renal obstruction.
    • This method aids in the diagnosis of pediatric hydronephrosis.