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Atropine-selective membrane electrodes and relative selectivity concept.

Mohsen M Zareh¹

¹Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt. mohsenzareh@hotmail.com

Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry

|July 11, 2008

Summary

This study introduces TFPB as a charged ionophore for atropine selective electrodes, achieving Nernstian responses and wide linear ranges for atropine detection. A novel "Relative Selectivity Concept" was also developed and applied.

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Area of Science:

Analytical Chemistry
Electrochemistry
Chemical Sensors

Background:

Development of selective electrodes for ion detection is crucial in analytical chemistry.
Atropine detection requires sensitive and selective electrochemical methods.
Existing ionophores and selectivity assessment methods have limitations.

Purpose of the Study:

To introduce Tetrakis(4-fluorophenyl) borate (TFPB) as a novel charged ionophore for atropine selective electrodes.
To evaluate the performance of PVC-membrane electrodes with different plasticizers for atropine sensing.
To introduce and apply a new
Relative Selectivity Concept

Main Methods:

Fabrication and characterization of poly(vinyl chloride) (PVC)-membrane electrodes.
Incorporation of TFPB as a charged ionophore and NPOE, DOS, DDP as plasticizers.
Electrochemical measurements including Nernstian response, linear range, optimum pH, and selectivity coefficient determination.

Main Results:

Typical Nernstian responses (57.78-58.95 mV/decade) were observed for the developed electrodes.
Practical linear ranges extended down to 10(-6) - 10(-7) M atropine concentrations.
The new
Relative Selectivity Concept

Conclusions:

TFPB is an effective charged ionophore for atropine selective electrodes.
The developed electrodes demonstrate good sensitivity and selectivity for atropine detection.
The
Relative Selectivity Concept