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[Functions of protein MTS1 (S100A4) in normal and tumor cells]

Iu A Koshelev, G P Georgiev, A V Kibardin

    Genetika
    |July 16, 2008
    PubMed

    Insights

    The protein MTS1 (multiple tissue inhibitor of metalloproteinase 1) plays a key role in regulating cell motility and metastasis development. This review summarizes current knowledge on MTS1

    Area of Science:

    • Molecular Biology
    • Cell Biology
    • Oncology

    Context:

    • The protein MTS1 (multiple tissue inhibitor of metalloproteinase 1) is implicated in metastasis and cell motility.
    • Its structure, gene, and expression regulation are well-studied.
    • Molecular mechanisms involving MTS1 are increasingly understood.

    Purpose:

    • To review the current knowledge on the protein MTS1.
    • To consolidate findings on MTS1's role in normal and pathological conditions.
    • To highlight advances in understanding MTS1's molecular mechanisms.

    Summary:

    • Extensive evidence links MTS1 to metastasis development and cell motility regulation.
    • Detailed studies cover MTS1's structure, gene, and expression.
    • Significant progress has been made in elucidating MTS1's molecular functions.

    Impact:

    • Provides a comprehensive overview of MTS1 research.
    • Facilitates understanding of cancer metastasis and cell movement.
    • Serves as a reference for future research on MTS1 and related pathways.

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