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Decrease in prevalence of Helicobacter pylori infection during a 10-year period in Brazilian children
Arquivos De Gastroenterologia
|July 16, 2008
Summary
Helicobacter pylori infection prevalence significantly decreased in children over a 10-year period, particularly in younger age groups and those with epigastric pain. This study tracked H. pylori trends in pediatric endoscopy patients.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Epidemiology
Background:
- Global reports indicate a declining prevalence of Helicobacter pylori (H. pylori) infection.
- Understanding H. pylori trends in pediatric populations is crucial for public health.
- This study investigates H. pylori infection rates in children undergoing endoscopy.
Purpose of the Study:
- To evaluate the prevalence of Helicobacter pylori infection over a 10-year period in children.
- To assess trends in H. pylori infection among pediatric patients undergoing upper digestive endoscopy.
- To identify age-specific and symptom-related patterns in H. pylori prevalence.
Main Methods:
- Retrospective observational study of 1,165 pediatric endoscopies (age ≤ 18) over 10 years.
- H. pylori infection diagnosed via rapid urease test on antral mucosal biopsy.
- Chi-square for trend analysis used to compare prevalence over time.
Main Results:
- Overall H. pylori prevalence was 33.6% (392/1165).
- Prevalence decreased from 60.47% in the first year to 30.43% in the last year.
- Significant decreases observed in children under 6 and over 12, and notably in those with epigastric pain.
Conclusions:
- A significant decline in H. pylori infection prevalence was observed in the studied pediatric cohort.
- The reduction in H. pylori infection was most pronounced in younger children and those presenting with epigastric pain.
- Findings suggest a positive trend in controlling H. pylori in pediatric populations.
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