L-tryptophan-associated eosinophilia-myalgia syndrome: perspective of a new illness

The current knowledge of the eosinophilia-myalgia syndrome as an evolving new disease entity is reviewed in the context of previously described eosinophilic disorders. The acute and chronic manifestations parallel the findings of the toxic oil syndrome of Spain and include scleroderma-like skin disease, neuropathy, and myopathy.