Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
Dysrhythmias I: Introduction01:15

Dysrhythmias I: Introduction

Dysrhythmias refers to abnormalities in the heart's rhythm. They result from disruptions in the heart's electrical conduction system, which includes the sinoatrial(SA)node, atrioventricular(AV) node, the bundle of His, bundle branches, and Purkinje fibers.Definition and PathophysiologyDysrhythmias result from disorders of impulse formation, impulse conduction, or both. The heart contains specialized cells in the sinoatrial node, atrioventricular node, and the bundle of His and Purkinje fibers...
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
Dysrhythmias II: Classification of Tachyarrhythmias01:28

Dysrhythmias II: Classification of Tachyarrhythmias

Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reference values of strain-derived myocardial work indices in heart transplant patients.

European heart journal. Imaging methods and practice·2024
Same author

Unveiling the reliability of left atrial strain measurement: a dedicated speckle tracking software perspective in controls and cases.

European heart journal. Imaging methods and practice·2024
Same author

Selenium Deficiency as a Risk Factor for Peripartum Cardiomyopathy.

West African journal of medicine·2024
Same author

A new biofeedback device to improve adherence to pelvic floor muscle training in women with urinary incontinence: a randomised controlled pilot trial (abridged secondary publication).

Hong Kong medical journal = Xianggang yi xue za zhi·2022
Same author

Disease progression in cardiac morphology and function in heart failure: ATTR cardiac amyloidosis versus hypertensive left ventricular hypertrophy.

Heart and vessels·2022
Same author

Advances in nanotechnology-based strategies for the treatments of amyotrophic lateral sclerosis.

Materials today. Bio·2020
Same journal

Feasibility of early double sequential defibrillation in out-of-hospital cardiac arrest: the double-D randomised pilot trial.

Heart (British Cardiac Society)·2026
Same journal

Correspondence on 'When a patent foramen ovale becomes pathological' by Saji and Ohara.

Heart (British Cardiac Society)·2026
Same journal

Cost-effectiveness of N-terminal pro-B-type natriuretic peptide thresholds for echocardiography referral in primary care heart failure management.

Heart (British Cardiac Society)·2026
Same journal

Optimal timing of aspirin discontinuation after acute coronary syndrome treated with percutaneous coronary intervention: a systematic review and meta-analysis.

Heart (British Cardiac Society)·2026
Same journal

Importance of rating: the impact of establishing age and sex normative values for left ventricular strain rate.

Heart (British Cardiac Society)·2026
Same journal

Man in his 40s with palpitations.

Heart (British Cardiac Society)·2026
See all related articles

Related Experiment Video

Updated: Jul 3, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Beyond dyssynchrony in cardiac resynchronisation therapy.

R Chung1, R Sutton, M Y Henein

  • 1Royal Brompton Hospital, London, UK.

Heart (British Cardiac Society)
|July 16, 2008
PubMed
Summary
This summary is machine-generated.

Cardiac resynchronisation therapy (CRT) improves heart failure by synchronising ventricular contractions. However, one-third of patients may not see global benefits, suggesting other factors influence outcomes.

More Related Videos

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
08:43

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Published on: August 26, 2021

Related Experiment Videos

Last Updated: Jul 3, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
08:43

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Published on: August 26, 2021

Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • Refractory heart failure presents a significant clinical challenge.
  • Cardiac resynchronisation therapy (CRT) using biventricular pacing is a therapeutic option.
  • Patient selection for CRT relies on assessing ventricular dyssynchrony.

Purpose of the Study:

  • To explore the effectiveness of CRT in heart failure patients.
  • To identify factors beyond dyssynchrony that impact CRT outcomes.

Main Methods:

  • Utilized electrocardiogram (ECG) and echocardiography to measure electromechanical ventricular dyssynchrony.
  • Analyzed pressure relations and timing abnormalities in heart failure patients.

Main Results:

  • CRT aims to minimize isovolumic time and maximize diastolic filling time for improved cardiac output.
  • Approximately one-third of patients receiving CRT do not achieve global improvement.
  • Dyssynchrony correction alone is insufficient for optimal outcomes in a subset of patients.

Conclusions:

  • While CRT is beneficial, patient selection and optimization require further refinement.
  • Understanding pressure dynamics and abnormal timing is crucial for enhancing CRT efficacy.
  • Comprehensive clinical management strategies are essential for maximizing positive outcomes in CRT patients.