Related Experiment Video
Updated: Jul 3, 2026

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
Published on: May 10, 2022
Interactions between eating disorders and drug abuse
Debra L Franko1, David J Dorer, Pamela K Keel
1Department of Psychiatry, Harris Center for Eating Disorders, Massachusetts General Hospital, Boston, MA 02114, USA. d.franko@neu.edu
Drug abuse did not affect recovery from anorexia nervosa or bulimia nervosa in women. However, alcohol use, suicide attempts, and prior hospitalizations predicted drug use disorder in these patients.
Area of Science:
- Psychiatry
- Addiction Medicine
- Clinical Psychology
Background:
- Eating disorders and drug abuse frequently co-occur, posing complex clinical challenges.
- Understanding the interplay between substance use and eating disorder recovery is crucial for effective treatment.
Purpose of the Study:
- To investigate the longitudinal relationship between drug use disorder (DUD) and recovery from anorexia nervosa (AN) and bulimia nervosa (BN).
- To identify predictors of DUD in women with eating disorders.
Main Methods:
- Prospective longitudinal study of 136 women with AN and 110 women with BN.
- Regular assessments for DUD every 6-12 months over an 8.6-year period.
- Multivariate analyses to determine the influence of DUD on recovery and to identify predictive factors.
Main Results:
- Drug use disorder (DUD) did not significantly impact recovery rates for either anorexia nervosa (AN) or bulimia nervosa (BN).
- In AN, predictors of DUD included alcohol use, suicide attempts, and prior hospitalization for affective disorders.
- In BN, predictors of DUD included severity of alcohol use, severity of bulimic symptoms, and prior hospitalization for nonaffective disorders.
Conclusions:
- Drug abuse does not appear to hinder recovery from anorexia nervosa or bulimia nervosa.
- Specific factors like alcohol use, suicide attempts, and psychiatric history predict drug use disorder in women with eating disorders.
- Routine monitoring for drug abuse is recommended for women with eating disorders due to clinical significance.
Related Concept Videos
Drug Abuse and Addiction: Pharmacological Phenomena
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Bulimia Nervosa
Drug toxicity: Drug–Drug Interaction
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Pharmacokinetics: Drug–Food and Drug–Viral Interactions

