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Updated: Jul 3, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
Systemic lupus erythematosus with generalized chronic cutaneous (discoid) lupus erythematosus
Chicky Dadlani1, Melissa Pulitzer, Stephen D Prystowsky
1Department of Dermatology, New York University, USA.
Abstract:
A 24-year-old pregnant African-American woman had a 3-4 year history of chronic, scarring, hyperpigmented plaques on her scalp, face, trunk, and extremities. She complained of joint pain and fatigue. Clinical presentation, laboratory data, and histopathologic features were consistent with systemic lupus erythematosus in a patient with generalized chronic discoid lupus erythematosus. This subtype is a distinct lupus erythematosus subset that rarely develops renal disease and has a relatively benign but chronic course.
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