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An autopsy case of I-cell disease. Ultrastructural and biochemical analyses
H Kitagawa1, J Toki, T Morimoto
1First Department of Pathology, Kansai Medical University, Osaka, Japan.
American Journal of Clinical Pathology
|August 1, 1991
Abstract:
An autopsy case of I-cell disease in a 4-year-old Japanese girl is presented. In this report, the authors analyze the relationship between morphologic (including electron microscopic) and biochemical findings. Lymph node, spleen, and kidney, which were stained with Hale's colloidal iron method, contained large amounts of hexosamine. These substances had accumulated in lymphocytes of B-cell lineage.