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With a little help from their friends: interleukin-21, T cells, and B cells

Jonathan S Silver1, Christopher A Hunter

  • 1Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Room 313, Hill Pavillion, 380 South University Avenue, Philadelphia, PA 19104-4539, USA.

Immunity
|July 18, 2008
PubMed

T follicular cells help B cells generate high-affinity antibodies. Two papers in this issue of Immunity (Nurieva et al., 2008, and Vogelzang et al., 2008) have identified a role for interleukin-21 in the development of these specialized cells and highlight questions about how this dedicated population is generated.

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