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Updated: Jul 3, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
Intestinal bladder augmentation at school age has no adverse effects on growth
Seppo Taskinen1, Outi Mäkitie, Riitta Fagerholm
1Department of Pediatric Surgery, Hospital for Children and Adolescents, University of Helsinki, Stenbäckinkatu 11, 00290 Helsinki, Finland. seppo.taskinen@hus.fi
Purpose:
Intestinal bladder augmentation predisposes the patient to many complications. The aim of this study was to determine whether augmentation has an adverse effect on growth.
Materials And Methods:
Longitudinal growth data were collected and analyzed for nine patients with bladder exstrophy and augmentation, and compared with the growth data of 13 exstrophy patients without augmentation. Augmentation was performed at a median age of 10.3 years (range 6.3-13.2). The median follow up was 5.4 years (range 3.6-9.1).
Results:
The median height Z-score at age 10 years was -0.4 (range -1.8 to +1.5) in patients who later received augmentation and -0.2 (-2.1 to +1.7) in the non-augmented group. Their median heights at latest follow up were -0.7 (-1.6 to +1.9) and 0.0 (range -1.8 to +1.1), respectively. The adult height of three patients with and 13 patients without augmentation was normal.
Conclusions:
Intestinal bladder augmentation performed at school age has no adverse effects on longitudinal growth in patients with bladder exstrophy. Most of the patients with bladder exstrophy have normal growth.
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