Tuberculous infection in Saharia, a primitive tribal community of Central India

V G Rao1, P G Gopi, R Yadav

  • 1Regional Medical Research Centre for Tribals, Indian Council of Medical Research, Nagpur Road, P.O. Garha, Jabalpur 482 003, India. drvgrao@rediffmail.com

Insights

Tuberculous infection is highly prevalent among Saharia children in India, with a high annual risk of tuberculosis infection (ARTI). Urgent, intensified tuberculosis control measures are needed for this vulnerable ethnic group.

Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • Tuberculosis remains a significant global health challenge, particularly in resource-limited settings.
  • Primitive ethnic groups often face unique vulnerabilities and health disparities.
  • Understanding tuberculosis infection dynamics in such populations is crucial for effective control.

Purpose of the Study:

  • To estimate the prevalence of tuberculous infection in Saharia children.
  • To determine the annual risk of tuberculosis infection (ARTI) in this population.
  • To inform targeted tuberculosis control strategies for primitive ethnic groups.

Main Methods:

  • A cross-sectional tuberculin survey was conducted among 1341 Saharia children aged 1-9 years.
  • Tuberculin testing was performed using 1 TU of PPD RT 23, with reactions read after 72 hours.
  • Data analysis included assessing BCG scar status and reaction size distribution.

Main Results:

  • The prevalence of tuberculous infection was estimated at 20.4% (95% CI 18.2-22.5%).
  • The annual risk of tuberculosis infection (ARTI) was found to be 3.9% (95% CI 3.5-4.3%).
  • Prevalence and ARTI remained high regardless of BCG scar status.

Conclusions:

  • The Saharia ethnic group exhibits a high prevalence of tuberculous infection and ARTI.
  • There is an urgent need to intensify tuberculosis control measures in this population.
  • Sustained, long-term interventions are essential for effective tuberculosis management.

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...