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Updated: Jul 3, 2026

Laser Microdissection Applied to Gene Expression Profiling of Subset of Cells from the Drosophila Wing Disc
Published on: April 30, 2010
[Dynamic filtration of the variability of expression patterns of zygotic segmentation genes in Drosophila]
Abstract:
An analysis of the quantitative data obtained by processing the confocal images showed that the early variability of expression patterns of zygotic segmentation genes in Drosophila drastically decreases by the time of the onset of gastrulation. The following components of variability were examined: the scatter of the levels of gene expression in different embryos, the time and sequence of the formation of expression domains, the type of their formation, and the domain positioning. It was found that the positioning error at the level of zygotic genes is dynamically filtered with time.

