Related Experiment Video
Updated: Jul 3, 2026
08:17
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
Psoriasis and chronic obstructive pulmonary disease: a case-control study.
J Dreiher1, D Weitzman, J Shapiro
1Hospital Division, Clalit Health Services, Tel-Aviv, Israel. jacod@bgu.ac.il
The British Journal of Dermatology
|July 22, 2008
Summary
Psoriasis is linked to a higher prevalence of Chronic Obstructive Pulmonary Disease (COPD). This study highlights the importance of managing smoking and other risk factors in psoriasis patients to mitigate COPD risk.
Area of Science:
- Dermatology
- Pulmonology
- Epidemiology
Background:
- Psoriasis and metabolic syndrome share associations.
- Chronic Obstructive Pulmonary Disease (COPD) is also linked to metabolic syndrome.
Purpose of the Study:
- To investigate the association between psoriasis and COPD.
- Utilizing a population-based case-control design.
Main Methods:
- Compared 12,502 psoriasis cases with 24,287 controls.
- Utilized Clalit Health Services database in Israel.
- Adjusted for age, sex, socioeconomic status, smoking, and obesity via logistic regression.
Main Results:
- COPD prevalence was significantly higher in psoriasis patients (5.7% vs. 3.6%).
- Psoriasis showed a significant association with COPD (OR 1.63).
- Multivariate analysis confirmed psoriasis association with COPD (adjusted OR 1.27).
Conclusions:
- Psoriasis is significantly associated with COPD in a large population.
- Dermatologists should consider COPD risk in psoriasis patients.
- Advise smoking cessation and risk factor reduction for COPD prevention.
Related Concept Videos
01:23Chronic Obstructive Pulmonary Disease I: Introduction
Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
01:24Chronic Obstructive Pulmonary Disease
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History