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Published on: July 14, 2023
Severe jaw enlargement associated with uremic hyperparathyroidism.
Faissal Tarrass1, Meryem Benjelloun, Tarik Bensaha
1Department of Nephrology & Dialysis, Hassani Hospital, Nador, Morocco. faissal76@hotmail.com
Hemodialysis International. International Symposium on Home Hemodialysis
|July 22, 2008
Summary
Marked jaw enlargement, a rare complication of renal osteodystrophy, can manifest as a localized mandibular brown tumor. This condition is associated with secondary hyperparathyroidism in patients undergoing chronic hemodialysis.
Area of Science:
- Nephrology
- Endocrinology
- Oral Surgery
Background:
- Renal osteodystrophy is a skeletal disorder resulting from chronic kidney disease.
- Secondary hyperparathyroidism commonly occurs in patients with chronic kidney disease.
- Jaw involvement is an uncommon but significant manifestation of renal osteodystrophy.
Observation:
- A case report details a patient on chronic hemodialysis presenting with localized mandibular enlargement.
- The enlargement was attributed to a brown tumor, a manifestation of secondary hyperparathyroidism.
- This highlights a rare complication of advanced kidney disease.
Findings:
- Brown tumors, characterized by osteoclast activity and reparative fibrosis, can occur in the jaws.
- Mandibular localization of brown tumors is infrequent but clinically relevant.
- The case underscores the systemic effects of secondary hyperparathyroidism.
Implications:
- Early recognition of jaw lesions is crucial for managing patients with renal osteodystrophy.
- Dental and medical professionals should be aware of this potential complication.
- Further research may elucidate optimal management strategies for jaw tumors in dialysis patients.
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