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Systemic therapy of paediatric atopic dermatitis: an update
Kate L A Borchard1, David Orchard
1Department of Dermatology, Royal Children's Hospital, Parkville, Victoria, Australia.
Topical treatments work for mild atopic dermatitis. For severe or widespread cases, systemic therapies like immunosuppressants and anti-inflammatories are reviewed for their indications and scientific support.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Topical therapies are standard for mild atopic dermatitis.
- Widespread or severe atopic dermatitis often necessitates systemic treatments.
Purpose of the Study:
- To review the indications for systemic therapies in atopic dermatitis.
- To examine the scientific evidence supporting systemic treatments for atopic dermatitis.
Main Methods:
- Literature review of systemic therapies for atopic dermatitis.
- Analysis of scientific support for various medication classes.
Main Results:
- Systemic therapies include immunosuppressants, immune response modifiers, anti-inflammatories, antihistamines, and antibiotics.
- Review covers indications and evidence for these systemic agents.
Conclusions:
- Systemic therapies are crucial for managing moderate to severe atopic dermatitis.
- Understanding indications and evidence is key for effective treatment selection.
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