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Updated: Jul 3, 2026

Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
Clinical trials of treatment for personality disorders
1Institute of Community and Family Psychiatry, Sir Mortimer B. Davis Jewish General Hospital, Department of Psychiatry, McGill University, 4333 Cote Ste-Catherine Road, Montreal, QC H3T 1E4, Canada. joel.paris@mcgill.ca
Abstract:
The objective of this review is to examine clinical trials of the treatment of personality disorders (PDs). The method is a narrative review of published controlled trials of psychotherapy and pharmacotherapy. Results show that a variety of methods reduce impulsivity, with less striking results for affective instability. There is good support for well-structured methods of psychotherapy, mainly in borderline personality disorder (BPD), but evidence for the efficacy of pharmacotherapy is weak. Research on other PD categories is sparse.
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