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Related Experiment Video

Updated: Jul 3, 2026

A Choroid Plexus Epithelial Cell-based Model of the Human Blood-Cerebrospinal Fluid Barrier to Study Bacterial Infection from the Basolateral Side
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Choroid plexus papillomas in childhood.

S Kennedy1, A Hanieh, B Clark

  • 1Department of Histopatholgy, Adelaide Children's Hospital, Division of the Women's and Children's Hospital, North Adeilade, Australia.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|October 1, 1995
PubMed
Summary

Choroid plexus papillomas are rare intracranial tumors, accounting for less than 5% of childhood tumors. These two pediatric cases highlight the diverse clinical presentations and outcomes of this benign tumor.

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Area of Science:

  • Neuro-oncology
  • Pediatric Neurosurgery
  • Pathology

Background:

  • Choroid plexus papillomas (CPPs) are rare intracranial neoplasms, constituting a small fraction of all tumors.
  • They represent less than 5% of pediatric brain tumors, underscoring their relative infrequency.
  • Understanding their presentation is crucial due to potential for varied clinical courses.

Purpose of the Study:

  • To report two pediatric cases of choroid plexus papilloma.
  • To illustrate the variability in clinical presentation, tumor location, and neurological outcomes.
  • To contribute to the understanding of this rare benign intracranial tumor in children.

Main Methods:

  • Case report methodology was employed.
  • Clinical data, imaging findings, and follow-up information were reviewed.
  • Detailed analysis of two distinct pediatric cases was performed.

Main Results:

  • Two pediatric patients with choroid plexus papilloma were identified.
  • Significant variability in clinical presentation and tumor location was observed between the cases.
  • Neurological outcomes differed, with one case followed for 13 years, indicating potential for long-term management.

Conclusions:

  • Choroid plexus papillomas, though rare, exhibit considerable variability in pediatric cases.
  • Clinical presentation and location do not always predict neurological outcome.
  • Long-term follow-up is essential for managing these benign tumors effectively.