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Choroid plexus papillomas in childhood
1Department of Histopatholgy, Adelaide Children's Hospital, Division of the Women's and Children's Hospital, North Adeilade, Australia.
Insights
Choroid plexus papillomas are rare intracranial tumors, accounting for less than 5% of childhood tumors. These two pediatric cases highlight the diverse clinical presentations and outcomes of this benign tumor.
Area of Science:
- Neuro-oncology
- Pediatric Neurosurgery
- Pathology
Background:
- Choroid plexus papillomas (CPPs) are rare intracranial neoplasms, constituting a small fraction of all tumors.
- They represent less than 5% of pediatric brain tumors, underscoring their relative infrequency.
- Understanding their presentation is crucial due to potential for varied clinical courses.
Purpose of the Study:
- To report two pediatric cases of choroid plexus papilloma.
- To illustrate the variability in clinical presentation, tumor location, and neurological outcomes.
- To contribute to the understanding of this rare benign intracranial tumor in children.
Main Methods:
- Case report methodology was employed.
- Clinical data, imaging findings, and follow-up information were reviewed.
- Detailed analysis of two distinct pediatric cases was performed.
Main Results:
- Two pediatric patients with choroid plexus papilloma were identified.
- Significant variability in clinical presentation and tumor location was observed between the cases.
- Neurological outcomes differed, with one case followed for 13 years, indicating potential for long-term management.
Conclusions:
- Choroid plexus papillomas, though rare, exhibit considerable variability in pediatric cases.
- Clinical presentation and location do not always predict neurological outcome.
- Long-term follow-up is essential for managing these benign tumors effectively.
Abstract:
Chroid plexus papillomas account for only 0.4-0.6% of intracranial tumours at all ages and less than 5% in childhood. Two paediatric cases are reported to demonstrate the variability in clinical presentation, location and neurological outcome of this benign tumour. One case has been followed for 13 years.
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