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Hunter syndrome complicated by hydrocephalus and an endogenous anticoagulant
1Department of Neurology, Alfred Hospital, Prahran, Victoria 3181 Australia.
Abstract:
This case illustrates the features of Hunter syndrome (mucopolysaccharidosis type 2) complicated by hydrocephalus and a prolonged activated partial thromboplastin time (APTT). Ventriculo-peritoneal shunt insertion was performed but was complicated by an extradural haematoma which was successfully drained. Other neurological complications of Hunter syndrome include compressive cervical myelopathy, diffuse cerebral white matter changes and punctate lesions in the basal ganglia. This case is the first report of a coagulation defect in a patient with Hunter syndrome.
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