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Updated: Jul 3, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Novel biologic model for percutaneous renal surgery learning and training in the laboratory
Yi Zhang1, Tong-wen Ou, Jian-guo Jia
1Department of Urology, Xuanwu Hospital of Capital Medical University, Beijing, China. zhangge1@medmail.com.cn
Objectives:
To improve the learning and training of percutaneous renal access and intrarenal procedures with a biologic porcine kidney model.
Methods:
We set up a biologic bench model using a porcine kidney. The kidney was wrapped in a full-thickness skin flap with subcutaneous fascia and muscle and fixed to a wooden board with 2 long steel nails. The ureter was catheterized to inject radiologic contrast medium or normal saline. Percutaneous renal manipulations were then practiced on the model under radiographic or ultrasound guidance.
Results:
Urologists with "partial" experience in advanced endourologic surgery were trained using this model. Of the 33 trainees practiced the percutaneous hands-on manipulations on this model, 20 (60.6%) attained success in performing the whole percutaneous procedure. One to three percutaneous access tracts were established successfully on each kidney practiced on. Of the 42 attendants, 36 (85.7%) rated this model for simulation as "very helpful" or "helpful."
Conclusions:
The porcine kidney model we developed is simple and easy to build with readily available materials. It provides realistic and reproducible practice for percutaneous renal surgery in the laboratory.

