Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Exercise and Cardiovascular Response

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

Liver Physiology

Liver Physiology

The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can also...

Overview of Lipid Metabolism

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...

Exercise and Muscle Performance

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...

Muscle Recovery and Fatigue

Muscle Recovery and Fatigue

Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective response...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Relationships between physical activity, sedentary behaviour, sleep, and dementia: A systematic review and meta-analysis of cohort studies.

PloS one·2026

Same author

Individual variability in insulin sensitivity, visceral fat, and cardiorespiratory fitness in response to exercise in adolescents with obesity.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2026

Same author

Effects of exercise modalities on heart rate recovery and its association with cardiometabolic risk in adolescents with overweight or obesity.

PloS one·2025

Same author

Did I Take My Medication Today? Understanding Medication Self-Management for Adults With Intellectual Disabilities Through Participatory Research.

Journal of applied research in intellectual disabilities : JARID·2025

Same author

The association of motivational factors with weight loss and treatment time in a publicly funded weight management clinic.

Clinical obesity·2025

Same author

Management and impact of obesity in Canada: A real-world survey of people with obesity and their physicians.

Obesity pillars·2025

Search research articles

Related Experiment Video

Updated: Jul 3, 2026

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease

Published on: July 19, 2024

Exercise and the fatty liver.

Natasha A Spassiani¹, Jennifer L Kuk

¹School of Kinesiology and Health Science, York University, Toronto, ON, Canada.

Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme

|July 22, 2008

Summary

Physical activity shows promise for treating fatty liver disease, but more human studies are needed to understand its independent effects. This research highlights the importance of exercise in managing metabolic health and reducing disease risk.

Area of Science:

Hepatology
Metabolic Medicine
Exercise Physiology

Background:

Fatty liver disease is a growing global health concern linked to metabolic dysfunction.
Current research suggests physical activity may be a beneficial intervention for fatty liver.
However, longitudinal human studies are limited, often confounding exercise with diet and caloric restriction.

Purpose of the Study:

To review the existing evidence on the role of physical activity in managing fatty liver.
To highlight the need for further research into the independent effects of exercise on liver fat.
To explore the relationship between physical activity, liver fat, and risks for cardiovascular disease and type 2 diabetes.

Main Methods:

Systematic review of cross-sectional and longitudinal studies.

More Related Videos

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Published on: March 11, 2017

Related Experiment Videos

Last Updated: Jul 3, 2026

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease

Published on: July 19, 2024

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Published on: March 11, 2017

Analysis of intervention studies in humans and animal models (rats).

Examination of correlations between physical activity, liver fat, and metabolic disease risk factors.

Main Results:

Cross-sectional data suggest physical activity is associated with reduced liver fat.
Longitudinal human data are sparse, with most studies combining exercise with dietary changes.
Animal studies show exercise benefits liver fat, particularly under high-fat diets or obesity.

Conclusions:

Physical activity is a potential therapeutic target for fatty liver disease.
The independent contribution of physical activity to reducing liver fat requires further investigation.
Both physical activity and liver fat are independently associated with cardiovascular and type 2 diabetes risk, warranting consideration in metabolic disease management.