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Updated: Jul 3, 2026

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)
08:25

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Published on: January 17, 2020

New formulae for folding catalysts make them multi-purpose enzymes

M Moutiez1, R Guthapfel, P Gueguen

  • 1CEA, Département d'Ingénierie et d'Etudes des Protéines, Bâtiment 152, C.E. Saclay, F-91191 Gif-sur-Yvette, France; telephone: (33)1-69.08.76.48; fax: (33)1-69.08.90.71.

Biotechnology and Bioengineering
|July 22, 2008
PubMed
Summary

Immobilizing protein disulfide isomerase (PDI) and prolyl isomerase (PPI) on agarose beads overcomes limitations for large-scale protein folding. Modified enzymes enhance efficiency and enable new biochemical reactor designs.

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