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Relationship between early diastolic strain rate imaging and left ventricular geometric patterns in hypertensive
Hyungseop Kim1, Hyun-Ok Cho, Yun-Kyeong Cho
1Department of Internal Medicine, Keimyung University, Dongsan Medical Center, 194 Dongsan-Dong, Jung-Gu, Daegu, Republic of Korea. khyungseop@dsmc.or.kr
Insights
Hypertension impacts left ventricular (LV) geometry and function. Strain rate imaging (SRI) reveals that early diastolic strain rate (SR-e) is lowest in hypertensive individuals with concentric hypertrophy, correlating with LV mass index.
Area of Science:
- Cardiology
- Medical Imaging
- Hypertension Research
Background:
- Hypertension significantly alters left ventricular (LV) geometry and myocardial function.
- Strain rate imaging (SRI) shows promise for evaluating myocardial function.
Purpose of the Study:
- To investigate the correlation between SRI and LV geometric patterns in hypertensive individuals.
- To assess the utility of SRI in characterizing myocardial dysfunction in hypertension.
Main Methods:
- Conventional echocardiography, including LV mass index (LVMI), was performed on 51 hypertensive subjects and 21 controls.
- Tissue Doppler imaging (TDI) and SRI were acquired for all participants.
- Hypertensive subjects were categorized by LV geometric patterns.
Main Results:
- Hypertensive subjects exhibited enlarged left atrial dimensions and prolonged diastolic times.
- Lower TDI of early diastolic mitral annulus and SR-e were observed in hypertensives.
- SR-e values were significantly lower in hypertensive individuals with hypertrophy, particularly concentric hypertrophy, and correlated strongly with LVMI.
Conclusions:
- SRI, specifically SR-e, is a valuable tool for detecting altered systolic and diastolic function in hypertensive subjects.
- SR-e is closely associated with LV geometric patterns, especially LVMI, in hypertension.
- SRI can help characterize myocardial dysfunction related to hypertensive heart disease.
Abstract:
Hypertension is an important contributor to different left ventricular (LV) geometric patterns with resultant myocardial dysfunction. Strain rate image (SRI) has been suggested as a useful tool for the evaluation of myocardial function. The aim of this study was to assess whether SRI correlates with LV geometric patterns in hypertensive subjects. Fifty-one hypertensive subjects and 21 healthy controls were enrolled and examined with conventional echocardiography including LV mass index (LVMI). Moreover, tissue Doppler imaging (TDI) and strain or SRI were obtained in all subjects. The hypertensives were subanalyzed according to geometric patterns. The hypertensive subjects were more likely to have enlarged left atrial dimensions, prolonged decelerating time and isovolumic relaxation time, and showed a lower TDI of early diastolic mitral annulus and SRI of early diastolic component (SR-e). Among hypertensive subjects, there was a significant trend toward a lower value of SR-e in those with hypertrophy and SR-e was the lowest in the concentric hypertrophy than other geometric patterns. In addition, SR-e was associated most strongly with LVMI of LV other than echoparameters. The hypertrophic hypertensive subjects showed altered systolic and/or diastolic function. Moreover, SR-e appeared to be correlated most with geometric patterns according to LVMI.
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