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Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
Published on: August 18, 2023
Rabies in humans
1Mayo Clinic-Rochester, Rochester, Minnesota, USA.
This article explains the causes, symptoms, and prevention methods for human rabies after potential exposure. Learn about rabies etiology, clinical signs, and postexposure prophylaxis strategies.
Area of Science:
- Veterinary Medicine
- Infectious Diseases
- Public Health
Background:
- Rabies is a fatal viral zoonotic disease transmitted through saliva of infected animals.
- Understanding rabies transmission is crucial for preventing human cases.
Observation:
- This column reviews the origins and clinical presentation of rabies in humans.
- It also covers essential postexposure prophylaxis (PEP) measures.
Findings:
- The etiology of rabies involves the rabies virus (RABV) primarily transmitted via bites from infected mammals.
- Clinical manifestations range from prodromal symptoms to neurological and paralytic phases, ultimately leading to death if untreated.
Implications:
- Prompt and appropriate postexposure prophylaxis is critical for preventing rabies encephalitis after potential exposure.
- Public health awareness and animal control are key to reducing human rabies incidence.
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