Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Portal Hypertension01:22

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Intestinal manifestations of Behçet's disease].

Terapevticheskii arkhiv·2020
Same author

[Thrombotic microangiopathy in rheumatology: a link between thrombosis and autoimmunity].

Terapevticheskii arkhiv·2020
Same author

[Cognitive disorders in Behçet's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2019
Same author

Comparative analysis of anxiety-depressive spectrum disorders in patients with rheumatic diseases.

Terapevticheskii arkhiv·2019
Same author

[Neurological and psychiatric disorders in Behҫet's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2017
Same author

[Behçet's disease: Intracardiac thrombosis (a description of two cases and a review of literature)].

Terapevticheskii arkhiv·2017
Same journal

[Morphological Features of Mesenhymal Stroma Cells of Chorionic Villi].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2018
Same journal

[Cardiovascular Effects of Incretin-Based Therapies and Their Therapeutic Potential].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2018
Same journal

[Prospects for the Use of Cannabinoid Receptor Ligands for the Treatment of Metabolic Syndrome and Atherosclerosis: Analysis of Experimental and Clinical Data].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2018
Same journal

[The Primary Metatarsalgia: Pathogenesis, Biomechanics and Surgical Treatment].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2018
Same journal

[Complement System Abnormalities in Patients with Atypical Hemolytic Uremic Syndrome and Catastrophic Antiphospholipid Syndrome].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2018
Same journal

[Peculiarities of Allergy Diagnosis in Children].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2018
See all related articles

Related Experiment Video

Updated: Jul 3, 2026

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

[Behcet's disease].

Z S Alekberova

    Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
    |July 26, 2008
    PubMed
    Summary
    This summary is machine-generated.

    This study observed 83 patients with Behcet's disease (BD), a systemic vasculitis. Key findings include frequent major criteria, male predominance, and a strong association with HLA B5 antigen.

    More Related Videos

    Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
    06:15

    Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

    Published on: August 9, 2024

    A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
    07:50

    A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

    Published on: September 20, 2018

    Related Experiment Videos

    Last Updated: Jul 3, 2026

    Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
    07:27

    Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

    Published on: December 18, 2012

    Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
    06:15

    Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

    Published on: August 9, 2024

    A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
    07:50

    A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

    Published on: September 20, 2018

    Area of Science:

    • Rheumatology
    • Immunology
    • Neurology

    Context:

    • Behcet's disease (BD) is a rare systemic vasculitis with unknown etiology.
    • Its clinical manifestations are diverse, affecting multiple organ systems.
    • Understanding BD's presentation and associations is crucial for diagnosis and management.

    Purpose:

    • To describe the clinical characteristics and diagnostic criteria observed in 83 patients with Behcet's disease.
    • To investigate the frequency of major and minor diagnostic criteria.
    • To explore demographic and genetic associations, specifically gender distribution and HLA B5 antigen.

    Summary:

    • The study analyzed 83 Behcet's disease patients, noting frequent major criteria: aphthous stomatitis, genital ulcers, and ocular lesions.
    • Minor criteria like central nervous system (CNS) and gastrointestinal tract (GIT) disturbances, and vascular thromboses were also observed, significantly impacting prognosis.
    • Males were more frequently affected (1.7:1 ratio), and 85.5% of patients showed an association with the HLA B5 antigen.

    Impact:

    • Highlights the prevalence of specific diagnostic criteria in Behcet's disease patients.
    • Emphasizes the prognostic significance of CNS, GIT, and vascular involvement.
    • Reinforces the association between Behcet's disease and HLA B5, potentially aiding in genetic risk assessment.