[Main prognostic factors in locally spread rectal cancer]

Statistical analysis of 333 case histories has established main prognostic factors and their combinations determining general and recurrence-free survival of patients with locally spread rectal cancer. The one-factor analysis considered gender, age, prevalence degree, histological type of the tumor, operation volume, the presence of postoperative complications, non-adjuvant and adjuvant radiation therapy, chemotherapy, chemo-radiation therapy. Total survival in men was 51.3%, in women - 50.0% (p>0.05). In patients with local spread of rectal neoplasias the disease has systemic character and requires, when algorithm of treatment was determined for each patient, imperative use of schemes of combined and complex treatment including many components, since the surgical treatment only can not give satisfactory results.