Eosinophilic esophagitis in an asymptomatic Chinese

Area of Science:

• Gastroenterology
• Immunology
• Pathology

Background:

• Eosinophilic esophagitis (EoE) is increasingly prevalent in Western adults, presenting with symptoms like dysphagia and epigastric pain.
• Diagnosis relies on esophageal biopsy showing over 20 eosinophils/high-powered field and no gastric eosinophilia.

Observation:

• A case of eosinophilic esophagitis is reported in an asymptomatic adult male of Chinese ethnicity.
• This represents the first documented case of EoE in Asia.

Findings:

• The patient exhibited dense eosinophil infiltration in the esophagus.
• Crucially, the patient remained asymptomatic despite the significant eosinophilic presence.

Implications:

• This case challenges the typical symptomatic presentation of EoE.
• It suggests that esophageal eosinophilia can be asymptomatic, potentially impacting diagnosis and prevalence estimates in diverse populations.